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y 27632 and 6-[[5-fluoro-2-(3,4,5-trimethoxyanilino)-4-pyrimidinyl]amino]-2,2-dimethyl-4H-pyrido[3,2-b][1,4]oxazin-3-one

y 27632 has been researched along with 6-[[5-fluoro-2-(3,4,5-trimethoxyanilino)-4-pyrimidinyl]amino]-2,2-dimethyl-4H-pyrido[3,2-b][1,4]oxazin-3-one in 2 studies

Compound Research Comparison

Studies (y 27632)	Trials (y 27632)	Recent Studies (post-2010) (y 27632)	Studies (6-[[5-fluoro-2-(3,4,5-trimethoxyanilino)-4-pyrimidinyl]amino]-2,2-dimethyl-4H-pyrido[3,2-b][1,4]oxazin-3-one)	Trials (6-[[5-fluoro-2-(3,4,5-trimethoxyanilino)-4-pyrimidinyl]amino]-2,2-dimethyl-4H-pyrido[3,2-b][1,4]oxazin-3-one)	Recent Studies (post-2010) (6-[[5-fluoro-2-(3,4,5-trimethoxyanilino)-4-pyrimidinyl]amino]-2,2-dimethyl-4H-pyrido[3,2-b][1,4]oxazin-3-one)
1,924	3	891	27	1	22

Protein Interaction Comparison

Protein	Taxonomy	6-[[5-fluoro-2-(3,4,5-trimethoxyanilino)-4-pyrimidinyl]amino]-2,2-dimethyl-4H-pyrido[3,2-b][1,4]oxazin-3-one (IC50)
Chain A, Tyrosine-protein kinase SYK	Homo sapiens (human)	0.041
Chain A, Tyrosine-protein kinase SYK	Homo sapiens (human)	0.041
Chain A, Tyrosine-protein kinase BTK	Homo sapiens (human)	0.29
Chain A, Tyrosine-protein kinase BTK	Homo sapiens (human)	0.29
Chain A, Tyrosine-protein kinase BTK	Homo sapiens (human)	0.29
Chain A, Tyrosine-protein kinase BTK	Homo sapiens (human)	0.29
Chain A, Tyrosine-protein kinase BTK	Homo sapiens (human)	0.29
Chain A, Tyrosine-protein kinase BTK	Homo sapiens (human)	0.29
Tyrosine-protein kinase JAK2	Homo sapiens (human)	0.006
Tyrosine-protein kinase Lyn	Homo sapiens (human)	0.732
Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)	0.005
Dipeptidyl peptidase 4	Rattus norvegicus (Norway rat)	0.041
Tyrosine-protein kinase ZAP-70	Homo sapiens (human)	0.042
Tyrosine-protein kinase SYK	Homo sapiens (human)	0.167

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	1 (50.00)	2.80

Authors

Authors	Studies
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ	1
Duan, Y; Han, J; Liao, C; Xie, Z; Yang, X	1

Reviews

1 review(s) available for y 27632 and 6-[[5-fluoro-2-(3,4,5-trimethoxyanilino)-4-pyrimidinyl]amino]-2,2-dimethyl-4H-pyrido[3,2-b][1,4]oxazin-3-one

Article	Year
Small-Molecule Kinase Inhibitors for the Treatment of Nononcologic Diseases. Journal of medicinal chemistry, 2021, 02-11, Volume: 64, Issue:3 Topics: Animals; Autoimmune Diseases; Drug Discovery; Humans; Models, Molecular; Protein Kinase Inhibitors; Small Molecule Libraries	2021

Other Studies

1 other study(ies) available for y 27632 and 6-[[5-fluoro-2-(3,4,5-trimethoxyanilino)-4-pyrimidinyl]amino]-2,2-dimethyl-4H-pyrido[3,2-b][1,4]oxazin-3-one

Article	Year
Identification of potent Yes1 kinase inhibitors using a library screening approach. Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15 Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship	2013

Article

Year

Identification of potent Yes1 kinase inhibitors using a library screening approach.

Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013